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The vast majority (60.47%) of included articles were rated as "Critically Low" when only 34.88% and 4.65% of articles were rated as "Low" and "Moderate," respectively. This was largely caused by the fact that most articles did not display the information of excluded studies, which was one of the critical domains.
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Vitamin D deficiency (serum 25-hydroxyvitamin D [25(OH)D] < 50 nmol/L or 20 ng/ml) is associated with unfavorable skeletal outcomes, including fractures and bone loss. A 25(OH)D level of >50 nmol ...
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Blood glucose monitoring helps to identify patterns in the fluctuation of blood glucose (sugar) levels that occur in response to diet, exercise, medications, and pathological processes associated with blood glucose fluctuations, such as diabetes mellitus. Unusually high or low blood glucose levels can potentially lead to life …
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If serum ferritin levels are not elevated, a repeat measurement should be performed in 5 years to detect progression. 2,13 In p.C282Y homozygous persons who are 55 years of age or older and have ...
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This 12-week, single-arm, open-label study suggests that a facial serum, in combination with Purpose Gentle Wash and Purpose Dual Treatment Moisture Lotion, may be …
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About 70% of the zinc in circulation is bound to albumin, and any condition that alters serum albumin concentration can have a secondary effect on serum zinc levels. Although, serum zinc represents only 0.1% of the whole body zinc, the circulating zinc turns over rapidly to meet tissue needs.[ 6, 10, 11 ]
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Topical HA in a serum formulation provides excellent skin hydration, as demonstrated through clinical, photographic, chemical, and instrumental assessments. …
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Serum albumin levels, capillary blood sugar levels at admission, haemoglobin levels and duration of catheterization were significantly associated with CRBSI. …
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The term "hyperglycemia" is derived from the Greek hyper (high) + glykys (sweet/sugar) + haima (blood). Hyperglycemia is blood glucose greater than 125 mg/dL while fasting and greater than 180 …
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For depressive episodes and maintenance therapy, serum concentrations are recommended to be low as 0.4–0.6 mmol/L . The recommended serum levels for the treatment of mania are indicated at 0.4–0.8 mmol/L for ages 60–79 years and a bit lower (0.4–0.7 mmol/L) for patients with the age of 80 and above .
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Background Rheumatoid arthritis (RA) is an autoimmune disease of inflammatory joint damage, wherein C-reactive protein and autoantibodies including rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) are rapidly elevated. These serological factors are diagnostic markers of RA; however, their sensitivity and …
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It is the drug developer's responsibility to clarify what the supplied labels mean and to identify the correct questions and audits to ensure quality. The paper …
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This article provides a comprehensive review of serum protein electrophoresis, in- cluding a discussion of how the examination is performed, what it …
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SERUM PHOSPHATE AND CARDIOVASCULAR DISEASE IN ADVANCED CHRONIC KIDNEY DISEASE. ... This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) …
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Vitamin D is a fat-soluble vitamin that plays an important role in calcium homeostasis and bone metabolism. Vitamin D deficiency can lead to osteomalacia and rickets in children and osteomalacia in adults. …
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High serum total cholesterol (TC) ... We excluded 690 duplicates, and 5579 articles were deleted after assessing the title or abstract. After reviewing the full articles, another 126 papers were excluded, resulting in a meta-analysis of 14 articles. A manual search of the reference lists of these articles could not find any eligible studies.
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Iron deficiency anemia affects >1.2 billions individuals worldwide, and iron deficiency in the absence of anemia is even more frequent. Total-body (absolute) iron deficiency is caused by physiologically increased iron requirements in children, adolescents, young and pregnant women, by reduced iron intake, or by pathological …
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Vitamin B12 (cobalamin) is a water-soluble vitamin that is derived from animal products such as red meat, dairy, and eggs. Intrinsic factor is a glycoprotein that is produced by parietal cells in the stomach and is necessary for the absorption of B12 in the terminal ileum. Once absorbed, B12 is used as a cofactor for enzymes that are involved …
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Vitamin D supplementation can prevent and cure nutritional rickets in infants and children. Preclinical and observational data suggest that the vitamin D endocrine system has a wide spectrum of ...
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A nested case-control study of serum per- and polyfluoroalkyl substances and testicular germ cell tumors among U.S. Air Force servicemen. Environ Health …
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Serum vaccine antibody concentrations in children exposed to perfluorinated compounds. JAMA 307:391–397. [PMC free article] [Google Scholar] Grandjean P, Heilmann C, Weihe P, Nielsen F, Mogensen UB, Budtz-Jorgensen E. 2017. Serum vaccine antibody concentrations in adolescents exposed to perfluorinated compounds.
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In a prospective study, patients with hyponatremia more frequently reported a history of falling compared with people with normal serum sodium levels (23.8% vs 16.4%, respectively; P < .01) and had a higher rate of new fractures over a mean follow-up of 7.4 years (23.3% vs 17.3%; P < .004). Hyponatremia is a secondary cause of osteoporosis.
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The causal effect of serum calcium on myocardial infarction was also investigated by Zhou and colleagues using data from UK Biobank (9828 cases and 311,419 controls). They found that higher serum calcium was associated with higher risk for myocardial infarction (OR 1.99; p = 0.011). They also reported no causal relationship …
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In the investigation of the correlation between serum 25 (OH)D and all-cause mortality, as well as CVD mortality in hypertension, a total of 19,500 participants were included, with 52.59% being and a mean age of 58.8 years. The mean serum 25 (OH)D concentration, both before and after weighting, was 66.73 nmol/L and 71.32 …
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Introduction. Serum vitamin D is derived from skin exposure to the sun or dietary Vitamin D, including supplements D 2 and D 3.Serum vitamin D supports bone health, immune function, and absorption of …
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Hyperlipidemia is a condition that incorporates various genetic and acquired disorders that describe elevated lipid levels within the human body. Hyperlipidemia is extremely common, especially in the Western hemisphere, but also throughout the world. Alternatively, a more objective definition describes hyperlipidemia as low-density …
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Serum creatinine elevations have been observed, which although most often transient, require renal function monitoring. ... Bardin has published over 290 articles in international peer-reviewed journals, and has been the editor or co-editor of more than 30 books in the field of rheumatology, including Therapeutics in Rheumatology and the ...
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Introduction and background. Diabetes insipidus (DI) is a rare disorder, affecting roughly 1 in 25,000 people or about 0.004% of the global population [].Due to the rare occurrence in the population, the various forms of DI can be relatively neglected in medical education as well as in a research setting for improving clinical management []. ...
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Anemia is defined as hemoglobin below two standard deviations of the mean for the age and gender of the patient. Iron is an essential component of the hemoglobin molecule. The most common cause of anemia worldwide is iron deficiency, which results in microcytic and hypochromic red cells on the peripheral smear. Several causes of iron …
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2. Magnesium Absorption and Excretion. Magnesium homeostasis is regulated by the intestines, the bones, and the kidneys [].The majority of magnesium is absorbed by a passive paracellular mechanism in the ileum and distal parts of the jejunum, while a smaller amount is actively transported in the large intestine [2, 6].Around …
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